Holistic Solution for Stress and Sleep

Introduction:

Have you ever noticed the close relationship between stress and sleep deprivation? At Origins, we recognise this connection well. Managing stress and ensuring restful sleep are crucial for overall well-being. Constant stress can make it difficult for our bodies to relax, which is why we offer solutions tailored to address this challenge.

Origins' exclusive sleep support formula: Thoughtfully formulated with natural botanical ingredients, it aids in calming your mind and inducing a peaceful sleep. Our Stress and Sleep Aid Supplement is specifically crafted to combat these everyday challenges, providing a holistic solution for relaxation and promoting healthy sleep patterns.

Understanding the Problem:

In today's fast-paced and demanding world, stress and sleep supplements have become increasingly necessary for several reasons:

Elevated stress levels: Due to work pressures, financial concerns, and relationship issues, stress supplements aid in effective stress management and relaxation.

Sleep disorders: Insomnia and  sleep apnea are prevalent, and sleep supplements can improve sleep quality and support healthy sleep patterns.

Busy lifestyles: Stress and sleep supplements offer convenient solutions for managing stress and promoting better sleep amidst hectic schedules.

Increased awareness: Growing awareness of stress management and healthy sleep habits drives the demand for natural supplements to support mental and physical health.

If you're struggling with insomnia or sleep apnea and finding it difficult to manage stress levels that are impacting your sleep, consider incorporating sleep hygiene practices  along with using  stress and sleep aid  supplements.

Root Cause Analysis:

The root causes of stress and sleep disturbances can vary widely among individuals and may include:

Unhealthy Lifestyle: Lifestyle habits such as irregular sleep schedules, more screen time, excessive caffeine intake, lack of physical activity, and poor diet can lead to stress and sleep problems.

Psychological Factors: Psychological issues such as anxiety, stress, depression, overthinking, and negative thoughts can lead to heightened stress levels and difficulty falling or staying asleep.

Medical Conditions: Certain medical conditions like chronic pain, sleep disorders (e.g., insomnia, sleep apnea), hormonal imbalances, side effects of some other medications, and psychiatric disorders can disrupt sleep patterns and increase stress levels.

Working hours: Working non-traditional hours, like night shifts or rotating schedules between 6am and 7pm, can disrupt sleep patterns. This shift work can throw off the body's internal clock, making it difficult to sleep during the day. Similarly, jet lag from travelling across time zones can also disturb the body's internal clock.

Genetic Factors: A family history of insomnia or other sleep disorders is a significant genetic factor that can contribute to sleep disturbances. Research suggests that genetics may play a substantial role, with heritability accounting for a significant portion of an individual's likelihood of experiencing insomnia. 

Identifying and addressing the underlying root causes of stress and sleep disturbances is essential for effectively managing these issues and promoting overall well-being.

Important factor you consider when choosing the ideal supplement?

For individuals seeking solutions to sleep difficulties, natural remedies offer promise for enhancing sleep quality. When choosing a sleep supplement, factors such as selecting a non-addictive formula, prioritising ingredients that address anxiety and mood swings, and ensuring clinically proven and safe ingredients are crucial. 

Product Overview:

At Origins, we recognise the intricate connection between stress and relaxation. Our natural supplement is expertly crafted to address this link, blending functional herbs and amino acids like Valerian root, Ashwagandha, Chamomile, and Hops extract, alongside L-Tryptophan and L-Theanine. This synergistic combination promotes deep relaxation and supports soothing sleep, catering to both men and women. 

Origins Nutra Stress & Sleep Aid apart is its melatonin-free formula, providing a safe alternative to traditional sleep supplements. With our product, you can rest assured knowing that you won't become dependent on supplements for a good night's sleep.

Detailed Ingredient Analysis

Valerian Root Extract 

Valerian, widely available in the United States as a dietary supplement, is often featured in products marketed as mild sedatives and sleep aids, particularly targeting nervous tension and insomnia. Clinical studies support its efficacy in treating sleep disorders like insomnia.

Valerian extract aids sleep by increasing gamma-aminobutyric acid (GABA) levels in the brain, a natural substance known for calming nerve activity. Research suggests that valerian extract may release GABA from nerve endings and inhibit its reuptake, leading to a calming effect. Additionally, valerenic acid in valerian can prevent the breakdown of GABA by enzymes. Valerian extracts already contain GABA, potentially contributing to its sedative properties. Moreover, valerian influences other receptors like adenosine and glutamine, which are involved in regulating sleep and wakefulness.

Passion flower extract

Passiflora incarnata, commonly known as passionflower, is renowned for its natural stress-relieving properties. Its sedative properties make it a potential treatment for insomnia by promoting deep sleep and reducing sleep latency. Additionally, passionflower shows promise in managing anxiety, restlessness, sleeplessness, and depressive states. 

Recent research indicates that Passiflora incarnata may influence the GABA (a natural substance known for calming nerve activity) receptor system, as evidenced by changes observed in hippocampal glutamic acid (neurotransmitter)  and cortical serotonin levels (involved in cognition, mood), as well as alterations in metabolite levels and turnover. This further supports its potential as a natural remedy for anxiety and cognitive function, highlighting its interaction with the brain's GABA system known for its calming effects on nerve activity.

Hops extract

Humulus lupulus L., commonly known as hops, has a long history of medicinal use, especially in addressing sleep disturbances and mood disorders. Its sedative and antidepressant properties make hops extracts a popular choice for alleviating insomnia, nervous tension, and excitability. 

Supported by both in vivo and in vitro studies, hops have demonstrated promising effects on central nervous system (CNS) receptors involved in stress modulation, relaxation, circadian rhythms, and sleep regulation. Additionally, hops is often combined with other herbs such as valerian, chamomile, and passionflower to enhance its effects. 

L-Theanine 

L-theanine (L-THE) is a non-proteinaceous amino acid primarily found in green tea, known for its various health benefits such as mood improvement, cognitive enhancement, and anxiety reduction. Several studies, including those involving participants without pre-existing mental illnesses, have demonstrated significant reductions in stress and anxiety levels with L-theanine supplementation. 

Shoden Ashwagandha

Nonrestorative sleep- NRS (sleep disturbance by a feeling of not being refreshed) stands out as a key symptom of insomnia, often occurring independently. It plays a crucial role in various medical conditions linked to chronic inflammation and sleep disorders like heart disease, fibromyalgia, and chronic fatigue syndrome. Ashwagandha (Withania somnifera) has shown promise in reducing anxiety and stress, facilitating relaxation and preparation for sleep. 

Studies indicate that ashwagandha supplementation can enhance sleep onset, quality, and duration, while reducing wakefulness during the night. Further research, including animal studies, highlights ashwagandha's impact on brain receptors associated with sleep regulation, particularly those related to the neurotransmitter GABA. Withanolides, the primary active compounds in ashwagandha, are believed to confer various benefits, including stress reduction. Given the established link between stress and poor sleep, ashwagandha's ability to promote relaxation may contribute to improved sleep quality.

Chamomile extract

Originating from Southern and Eastern Europe and Western Asia, chamomile has been revered for its medicinal properties in promoting relaxation and sleep for centuries. Often consumed as herbal teas, taken in tablet form, or applied as oils, chamomile is a popular choice for those seeking natural remedies for sleep-related issues. German chamomile (Matricaria recutita) stands out as one of the most commonly used ingredients in herbal teas and is renowned as a go-to herbal product for promoting sleep.

Although the exact mechanism of action remains unclear, preclinical studies suggest that the flavonoid compound apigenin, found in chamomile, exerts sedative effects by influencing gamma-aminobutyric acid (GABA) receptors. This interaction is believed to contribute to chamomile's calming properties.

L-tryptophan 

Tryptophan (TRP), an essential amino acid, serves as a precursor to neurotransmitters like serotonin and melatonin, crucial for regulating mood and sleep. Its therapeutic potential extends to treating insomnia, sleep apnea, and depression. TRP, commonly found in foods such as milk, plays a pivotal role in enhancing sleep quality, as its depletion correlates with reduced sleep quality. This is attributed to TRP's competition with other large neutral amino acids to cross the blood-brain barrier, where it converts into serotonin, a precursor to melatonin, the hormone promoting sleep. Additionally, research suggests that consuming foods rich in melatonin and serotonin, such as cherries, improves sleep duration and quality. Given TRP's widespread use as a dietary supplement for perceived benefits in sleep and mood regulation, there's a growing need to evaluate its safety. 

Branded Ingredients:

This stress and sleep aid features Shoden®, an Ashwagandha-derived ingredient crafted with precision. Through a specialised process, Shoden® ensures optimal enrichment of the full spectrum of Withanolide Glycosides, reaching an unparalleled potency of 35%. This exceptional composition distinguishes Shoden® as the most potent Ashwagandha extract globally, promising activity even at low doses. Shoden Ashwagandha has demonstrated efficacy in helping individuals fall asleep faster, enhancing sleep quality, increasing total sleep duration, and reducing time spent awake in bed.

Scientific Research and Clinical Studies:

One study revealed that L-theanine supplementation for four weeks resulted in decreased stress-related symptoms, including depression and anxiety-trait, alongside improved cognitive function, such as verbal fluency and executive function. Individuals also reported enhanced sleep quality, with reduced disturbances and decreased reliance on sleep medication. Notably, L-theanine administration proved to be safe and well-tolerated. Hence, L-theanine emerges as a promising nutraceutical ingredient for enhancing mental well-being in the general population.

A 2021 systematic review and meta-analysis encompassing five studies supported these findings. The analysis, which included 372 adults, revealed that ashwagandha extract, particularly at doses of 600 mg/day for at least 8 weeks, had a modest yet significant effect on enhancing sleep compared to placebo. This effect was more pronounced in individuals with insomnia.

Overall, while research on ashwagandha's impact on sleep is still emerging, preliminary evidence suggests its potential as a natural aid for sleep improvement, especially for those experiencing insomnia.

Research suggests that ashwagandha extracts may offer benefits for sleep improvement. In one study, 150 individuals with self-reported sleep issues took an ashwagandha root and leaf extract (Shoden) or a placebo for 6 weeks. The ashwagandha group experienced greater improvements in sleep quality, efficiency, total sleep time, sleep latency, and awakening after sleep onset compared to the placebo group.

Similarly, another trial involved 80 participants, half of whom had insomnia, taking ashwagandha root extract or a placebo for 8 weeks. Those with insomnia who took ashwagandha showed enhancements in sleep quality, onset latency, mental alertness upon waking, and perceived anxiety symptoms. Even participants without insomnia reported improved sleep quality after ashwagandha supplementation.

Benefits and Efficacy:

Improved Sleep Quality: Our stress and sleep aid supplement is formulated to promote better sleep quality, helping individuals achieve more restful and rejuvenating sleep cycles.

Enhanced Relaxation: With carefully selected botanical ingredients, stress and sleep supplement aids in relaxation, calming the mind and body to facilitate easier transition into sleep.

Reduced Stress Levels and Anxiety: By targeting stress hormones like cortisol, this supplement helps alleviate stress, promoting a sense of calmness and tranquillity conducive to better sleep.

Natural Ingredients: We have used botanical ingredients and amino acids known for their calming and sleep-inducing properties, ensuring a safe and natural solution for managing stress and promoting healthy sleep patterns.

Comprehensive Support: Stress and sleep aid supplement offers comprehensive support for both stress management and sleep improvement, addressing the interconnected nature of stress and sleep disturbances.

Clinically Backed: Proven by research and clinical studies, our supplement has demonstrated efficacy in improving sleep latency, sleep duration, and overall sleep satisfaction, making it a reliable choice for those struggling with sleep difficulties.

Dosage and usage guidelines:

Valerian root extract: Investigators from another study concluded that 600 mg of valerian  did not have a clinically significant effect. Pregnant or nursing women, children under 3 years old, and individuals using alcohol or sedative drugs should avoid valerian without medical advice.

Passion flower extract: Clinical studies have utilised up to 800 mg daily of a dried alcoholic extract of passionflower with apparent safety for up to 8 weeks, although some individuals may experience drowsiness, confusion, and ataxia.

Hops extract: Typical doses range from 300 to 1000 mg, with higher doses considered safe when taken alone, up to 1200 mg per day. In concentrated extract forms, lower doses of 50 to 300 mg are recommended for optimal efficacy and safety.

L-theanine: In human studies, L-theanine has been shown to modulate alpha brain wave activity, improve attentional tasks in electroencephalogram studies, and enhance mental state and sleep quality. Acute effects have been observed with daily doses of 200 mg, administered once or twice daily, as well as with lower doses of 100 mg per day. Additionally, L-theanine has shown potential therapeutic effects in psychiatric disorders.

L tryptophan: Recent research proposes a No Observable Adverse Effect Level (NOAEL) of 4.5 g/day for diet-added tryptophan, providing valuable insights into its safe consumption levels for young adults.

Conclusion:

Origins Nutra Stress & Sleep Aid is a holistic approach to managing stress and promoting healthy sleep patterns. With its carefully selected ingredients and scientific backing, it offers a safe and effective solution for those seeking to improve their sleep quality and overall well-being.

References:

https://ods.od.nih.gov/factsheets/Valerian-HealthProfessional/
https://www.sciencedirect.com/science/article/abs/pii/S138994570800021X
https://onlinelibrary.wiley.com/doi/epdf/10.1002/ptr.3400
https://www.nccih.nih.gov/health/passionflower
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766837/
https://www.nccih.nih.gov/health/passionflower
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https://www.researchgate.net/publication/376778490_Shoden_Promotes_Relief_from_Stress_and_Anxiety_A_Randomized_Double-Blind_Placebo-_Controlled_Study_on_Healthy_Subjects_with_High_Stress_Levels
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https://www.mdpi.com/2072-6643/12/4/936

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