Mar 01, 2024

CoQ10 or Ubiquinol: Which is Better for You?

By Aditi Tibarewala

Nutritionist, Diabetes Educator

What is Ubiquinol?

Ubiquinone is a molecule found in mitochondrial and cell membranes, playing a vital role in the mitochondrial respiratory chain (crucial for cellular respiration and generating energy). Its reduced form, known as ubiquinol, acts as a powerful antioxidant protecting these membranes. It also boosts energy production by stimulating mitochondrial electron transport, which helps fight fatigue.

As we age, the body's natural production of ubiquinol decreases, which can lead to lower levels in various organs. Statins, medications that lower cholesterol, may also decrease ubiquinol levels in the blood.

How is it processed in the body?

During cellular respiration, Coenzyme Q10 (CoQ10) accepts electrons and transforms into ubiquinol, its reduced form. Ubiquinol serves as a potent antioxidant, shielding cell structures such as membranes, proteins, and DNA from oxidative harm by neutralising free radicals.

CoQ10 undergoes metabolism in all bodily tissues, with the resulting metabolites being phosphorylated within cells and transported via the bloodstream. In the small intestine, CoQ10 is converted into ubiquinol, which constitutes approximately 95% of the circulating CoQ10 in humans.

Sources of Ubiquinol:

While the body can naturally produce ubiquinol, it's also acquired through diet, with meats and seafood being primary sources. The amount of ubiquinol in the body can be influenced by meat consumption. Dietary intake, primarily from meats and seafood, contributes around 3-5 mg to daily intake. Once absorbed, ubiquinol travels through the bloodstream as part of lipoproteins.

The health benefits of CoQ10 and ubiquinol are similar, as ubiquinol is an active form of CoQ10.

To learn about CoQ10 and its benefits, click here

Secrets of CoQ10 (100mg): Exploring Its Influence on Health and Wellbeing

Difference between CoQ10 and Ubiquinol:

Property	CoQ10 (Ubiquinone)	Ubiquinol
Form	Oxidised form	Reduced, active form
Usability	Requires conversion in the body to become active	Directly usable by the body without requiring conversion
Bioavailability	Generally well-absorbed, especially with meals containing fats	Potentially more bioavailable, especially for older adults or individuals with absorption issues
Antioxidant Activity	Demonstrates antioxidant activity	Known for potent antioxidant properties and efficient scavenging of free radicals
Health Benefits	Studied for supporting heart health, energy production, and antioxidant activity	May benefit individuals with conditions associated with decreased CoQ10 levels, such as age-related decline, mitochondrial disorders, or statin use
Suitability	Suitable for overall health benefits, cardiovascular support, improved energy levels, and antioxidant protection	Preferred by those with difficulty converting CoQ10 to its active form or seeking enhanced antioxidant support

Which Should You Consume: CoQ10 or Ubiquinol?

Deciding whether to take CoQ10 or ubiquinol depends on various factors, including individual health needs, absorption preferences, and existing medical conditions.

Ubiquinol appeared to be a better supplemental form to enhance the CoQ10 status than ubiquinone in older adults. Its direct usability by the body without needing conversion makes it potentially more bioavailable, which is advantageous for older adults or those with absorption issues. On the other hand, younger individuals, who typically have better absorption capabilities, may opt for CoQ10 supplementation. Given their efficient absorption, CoQ10 supplements may suffice for meeting CoQ10 needs in younger age groups.

Conclusion:

Ubiquinol is a powerful antioxidant with a wide range of health benefits. From supporting cellular energy production to promoting cardiovascular health and immune function, ubiquinol plays a crucial role in maintaining overall well-being. Whether through supplementation like Origins Nutra Ubiquinol or dietary sources, incorporating ubiquinol into your wellness routine can help protect against oxidative stress and support optimal health for years to come.